Cell-Material Interaction

Cell-Material Interaction Photo

The interaction of material surfaces with cells is of primary relevance and contributes to the clinical success of implants. Cells sense their physico-chemical environment resulting in spatio-temporal localization, focal adhesion reorganization and activation of integrin dependent signaling proteins as well as phenotypic changes, e.g., of the actin cytoskeleton. The mechanics of building instructive biomaterials involves chemical modifications by grafting of chemical groups, growth factors and adhesion ligands. By structuring the surfaces geometrically and stochastically and by modifications of the material stiffness, physical modifications of the materials are designed. Insights into the mechanism at the interface that is included in the regulation of cells such as osteoblasts, stem cells and chondrocytes by materials will enhance the development of innovative biomaterials in regenerative medicine.

From the extracellular environment, cells can interpret information by turning physical cues into biochemical signals (mechanotransduction). Such physical cues may be in the form of topography (micro, macro, or nanoscale in size), surface chemistry (grafted or inherent) and stiffness (tissues have varying hardness from soft fat or nerve tissue to hard bone tissue). Cells alter their adhesion and cytoskeleton using cell adhesion sites in response to these extracellular cues. Adhesions and the cytoskeleton are inter-linked to biochemical effectors that can obtain control over cell migration, growth and even stem cell differentiation and self-renewal. This session will explore how we can utilize synthetic materials to explore the cell–material interface and how this has helps for tissue engineering next-generation scaffolds.

  • Biomaterial Surface Design
  • Responsive Materials and Surfaces
  • Analysis of Biointerfaces
  • Cell response to Surfaces
  • Self-assembly at Interfaces

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Cancellation, Postponement and Transfer of Registration

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All cancellations or modifications of registration must be made in writing to Program Manager(biomaterials@alliedmeetings.com and finance@alliedacademies.com) and the support number is  +44-2037691755 Extn 5041.

Cancellation Policy

If Allied academies cancel this event for any reason, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies Conferences (AAC) event which must occur within one year from the date of cancellation.

Postponement:

If Allied academies postpone an event for any reason and you are unable or unwilling to attend on rescheduled dates, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies Conferences event which must occur within one year from the date of postponement.

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All fully paid registrations are transferable to other persons from the same organization if registered person is unable to attend the event. Transfers must be made by the registered person in writing to Program Manager 
biomaterials@alliedmeetings.com and to our finance team finance@alliedacademies.com

Details must be included with the full name of replacement person, their title, contact phone number and email address. All other registration details will be assigned to the new person unless otherwise specified.

Registration can be transferred to one conference to another conference of Allied academies if the person is unable to attend one of conferences.

However, Registration cannot be transferred if it is intimated within 14 days of the respective conference.

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Refund policy:

If the registrant is unable to attend, and is not in a position to transfer his/her participation to another person or event, then the following refund arrangements apply:

Keeping in view of advance payments towards Venue, Printing, Shipping, Hotels and other overheads, we had to keep Refund Policy is as following slabs-

  •          Before 60 days of the conference: Eligible for Full Refund less $100 service Fee
  •                Within 60-30 days of Conference: Eligible for 50% of payment Refund
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