Implants are attaining popularity among the patients and are generally considered as a primary treatment option. Modern dentistry is emerging with the benefits of biomaterials in the healthcare sector. Research on materials sciences along with the biomechanics reveals optimization of design and material concepts for surgical implants. Biocompatibility is the prominent factor of implant material to demonstrate the favorable response in a biological environment. In the process of replacing a missing tooth, many biomaterials were discovered as implants which were an effort to create an optimal interaction between the living tissues and the implanted biomaterial.The key aspect is the prime importance of tissue response at the implant site which may cause a biochemical disturbance because of the presence of foreign materials.